A physical mechanism for large-ion selectivity of ion channels
نویسندگان
چکیده
a Department of Physiology and Biophysics, University of Miami School of Medicine, P. O. Box 016430, Miami, FL 33101, USA. E-mail: [email protected]; [email protected] b Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 86402-5700, USA. E-mail: [email protected] c Department of Molecular Biophysics and Physiology, Rush Medical College, 1750 W. Harrison St. #1291, Chicago, IL 60612, USA. E-mail: [email protected]
منابع مشابه
Simulation study of the transport properties of ions through ion channels serving as primary components of a nanobiosensor
Ion channels are naturally occurring pores through the proteins that regulate the passage of ions and thus maintain the concentration of ions inside and outside the cell. The ion channels control many physiological functions and they can show selectivity for a specific ion. Ion channels are mostly observed in nerve cells and muscle cells. The influx of ions into cells can be regulated by a gate...
متن کاملSimulation study of the transport properties of ions through ion channels serving as primary components of a nanobiosensor
Ion channels are naturally occurring pores through the proteins that regulate the passage of ions and thus maintain the concentration of ions inside and outside the cell. The ion channels control many physiological functions and they can show selectivity for a specific ion. Ion channels are mostly observed in nerve cells and muscle cells. The influx of ions into cells can be regulated by a gate...
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My collaborators and I [2] study selectivity in ion channels. Ion channels are proteins with a hole down their middle that are the (nano nearly pico)valves of life. Ion channels control an enormous range of biological function in health and disease. A large amount of data is available about selectivity in many channels. Selectivity in ion channels occurs without structural change of the channel...
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